New familial pain syndrome caused by TRPA1 mutation
نویسندگان
چکیده
منابع مشابه
A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome
Human monogenic pain syndromes have provided important insights into the molecular mechanisms that underlie normal and pathological pain states. We describe an autosomal-dominant familial episodic pain syndrome characterized by episodes of debilitating upper body pain, triggered by fasting and physical stress. Linkage and haplotype analysis mapped this phenotype to a 25 cM region on chromosome ...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2010
ISSN: 1759-4758,1759-4766
DOI: 10.1038/nrneurol.2010.97